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Toronto Liver Center

Toronto, Ontario, Canada
Eaton Building, 200 Elizabeth St, Toronto, ON M5G 2C4

About Toronto Liver Center


  • Top Sponsors
  • Top Collaborators
  • Trials By Phase
  • Recruitment Status
  • Top Conditions
  • Intervention Types
  • Top Intervention Names
  • Trials By Gender
Lead Sponsor
# Trials
University Health Network, Toronto
6
Gilead Sciences
3
Assembly Biosciences
2
Arbutus Biopharma Corporation
1
Calliditas Therapeutics Suisse SA
1
CymaBay Therapeutics, Inc.
1
Enanta Pharmaceuticals, Inc
1
F-star Therapeutics, Inc.
1
HighTide Biopharma Pty Ltd
1
Intercept Pharmaceuticals
1
Madrigal Pharmaceuticals, Inc.
1
Total Rows: 14

Clinical Trials at Toronto Liver Center


During the past decade, Toronto Liver Center conducted 12 clinical trials. In the 10-year time frame, 12 clinical trials started and 8 clinical trials were completed, i.e. on average, 66.7% percent of trials that started reached the finish line to date. In the past 5 years, 2 clinical trials started and 6 clinical trials were completed. i.e. 300% of trials that started reached the finish line.
Created with Highcharts 11.1.0TrialsTrials Trend - Last 10 Years1133333300111100110011222211Started TrialsCompleted Trails201620172018201920202021202201234
Trials List
Trail ID
Brief Title
Start Date
Completion Date
Status
Enrollment
Identification of the Genetic Variants Responsible for Primary Biliary Cirrhosis (PBC)
2004-08-01
Unknown status
500
Apoptosis and Hepatitis B: The Role of Apoptosis in Patients Who Are HBeAg Negative
2005-07-01
Unknown status
30
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis
2002-02-01
Unknown status
200
Neurocognitive Functioning in Patients With Hepatitis C Pre- and Post-Treatment With Antiviral Medication
2002-01-01
Unknown status
150
Insulin Resistance Associated With Chronic Hepatitis C (CHC) and the Effect of Antiviral Therapy
2003-08-01
Unknown status
200
Family Studies in Primary Biliary Cirrhosis (PBC)
2005-10-01
Unknown status
3,000
Hepatitis B Research Network Adult Cohort Study
2010-12-01
2021-06-09
Completed
2,051
Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis
2012-01-01
2018-12-17
Completed
217

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Clinical Trials Sponsors and Collaborators


Out of the total clinical trials conducted in "Toronto Liver Center" #1 sponsor was "University Health Network, Toronto" with 6 trials, followed by "Gilead Sciences" with 3 trials sponsored, "Assembly Biosciences" with 2 trials sponsored, "Arbutus Biopharma Corporation" with 1 trials sponsored and "Calliditas Therapeutics Suisse SA" with 1 trials sponsored. Other sponsors include 4 different institutions and companies that sponsored additional 14 trials in total.
In terms of collaborators to trials, out of the total clinical trials conducted in "Toronto Liver Center" #1 collaborator was "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)" with 2 trials as a collaborator, "National Center for Research Resources (NCRR)" with 1 trials as a collaborator, "PRA Health Sciences" with 1 trials as a collaborator, "Pharmaceutical Research Associates" with 1 trials as a collaborator and "Triangle Biostatistics" with 1 trials as a collaborator. Other collaborators include -4 different institutions and companies that were collaborators in the rest 6 trials.
Created with Highcharts 11.1.0Top Leading SponsorsUniversity HealthNetwork, Toronto: 6University HealthNetwork, Toronto: 6Gilead Sciences: 3Gilead Sciences: 3Assembly Biosciences: 2Assembly Biosciences: 2Arbutus BiopharmaCorporation: 1Arbutus BiopharmaCorporation: 1Calliditas TherapeuticsSuisse SA: 1Calliditas TherapeuticsSuisse SA: 1CymaBay Therapeutics, Inc.: 1CymaBay Therapeutics, Inc.: 1Enanta Pharmaceuticals, Inc: 1Enanta Pharmaceuticals, Inc: 1F-star Therapeutics, Inc.: 1F-star Therapeutics, Inc.: 1HighTide Biopharma Pty Ltd: 1HighTide Biopharma Pty Ltd: 1Intercept Pharmaceuticals: 1Intercept Pharmaceuticals: 1

Created with Highcharts 11.1.0Top CollaboratorsNational Institute ofDiabetes and Digestiveand Kidney Diseases(NIDDK): 2National Institute ofDiabetes and Digestiveand Kidney Diseases(NIDDK): 2National Center forResearch Resources(NCRR): 1National Center forResearch Resources(NCRR): 1PRA Health Sciences: 1PRA Health Sciences: 1PharmaceuticalResearch Associates: 1PharmaceuticalResearch Associates: 1Triangle Biostatistics: 1Triangle Biostatistics: 1University of Florida: 1University of Florida: 1

Clinical Trials Conditions at Toronto Liver Center


According to Clinical.Site data, the most researched conditions in "Toronto Liver Center" are "Hepatitis B" (7 trials), "Hepatitis C" (4 trials), "Biliary Cirrhosis, Primary" (2 trials), "Chronic Hepatitis B" (2 trials) and "Liver Cirrhosis, Biliary" (2 trials). Many other conditions were trialed in "Toronto Liver Center" in a lesser frequency.

Clinical Trials Intervention Types at Toronto Liver Center


Most popular intervention types in "Toronto Liver Center" are "Drug" (14 trials). Other intervention types were less common.
The name of intervention was led by "Placebo" (6 trials), "Placebo to match SEL 18 mg" (2 trials), "Placebo to match SEL 6 mg" (2 trials), "SEL" (2 trials) and "AB-836" (1 trials). Other intervention names were less common.

Clinical Trials Genders at Toronto Liver Center


The vast majority of trials in "Toronto Liver Center" are 22 trials for "All" genders.

Clinical Trials Status at Toronto Liver Center


Currently, there are NaN active trials in "Toronto Liver Center". undefined are not yet recruiting, 2 are recruiting, 2 are Active, not recruiting, and undefined are Enrolling by invitation. In total, there were 7 completed trials in Toronto Liver Center, undefined suspended trials, and 5 terminated clinical trials to date.
Out of the total trials that were conducted in Toronto Liver Center, 1 "Phase 1" clinical trials were conducted, 8 "Phase 2" clinical trials and 5 "Phase 3" clinical trials were conducted as well. "Phase 4" trials included 0 trials, and there were also 1 trials that are defined as “Not Applicable".
Created with Highcharts 11.1.0Trials By PhasePhase 2: 8Phase 2: 8Phase 3: 5Phase 3: 5Not Applicable: 1Not Applicable: 1Phase 1: 1Phase 1: 1

Created with Highcharts 11.1.0Trials StatusCompleted: 7Completed: 7Unknown status: 6Unknown status: 6Terminated: 5Terminated: 5Active, not recruiting: 2Active, not recruiting: 2Recruiting: 2Recruiting: 2