During the past decade, OrthoCarolina conducted 20 clinical trials. In the 10-year time frame, 20 clinical trials started and 7 clinical trials were completed, i.e. on average, 35% percent of trials that started reached the finish line to date. In the past 5 years, 9 clinical trials started and 5 clinical trials were completed. i.e. 55.6% of trials that started reached the finish line.

Out of the total clinical trials conducted in "OrthoCarolina" #1 sponsor was "OrthoCarolina Research Institute, Inc." with 7 trials, followed by "Zimmer Biomet" with 4 trials sponsored, "Smith & Nephew, Inc." with 3 trials sponsored, "BioMimetic Therapeutics" with 2 trials sponsored and "DePuy Orthopaedics" with 2 trials sponsored. Other sponsors include 10 different institutions and companies that sponsored additional 19 trials in total.

In terms of collaborators to trials, out of the total clinical trials conducted in "OrthoCarolina" #1 collaborator was "Charlotte Orthopedic Hospital" with 2 trials as a collaborator, "Alberta Children's Hospital" with 1 trials as a collaborator, "Alfred I. duPont Hospital for Children" with 1 trials as a collaborator, "Ann & Robert H Lurie Children's Hospital of Chicago" with 1 trials as a collaborator and "Baylor College of Medicine" with 1 trials as a collaborator. Other collaborators include 40 different institutions and companies that were collaborators in the rest 50 trials.

According to Clinical.Site data, the most researched conditions in "OrthoCarolina" are "Arthritis" (2 trials), "Osteoarthritis" (2 trials), "Osteoarthritis, Knee" (2 trials), "Rheumatoid Arthritis" (2 trials) and "Achilles Tendon Repairs/Reconstructions" (1 trials). Many other conditions were trialed in "OrthoCarolina" in a lesser frequency.

Most popular intervention types in "OrthoCarolina" are "Device" (16 trials), "Drug" (7 trials), "Procedure" (6 trials), "Other" (3 trials) and "Biological" (1 trials). Other intervention types were less common.

The name of intervention was led by "Placebo" (2 trials), "AUGMENT® Bone Graft" (1 trials), "Agilus" (1 trials), "Anterior Cervical Discectomy and Fusion" (1 trials) and "Basivertebral Nerve (BVN) Ablation" (1 trials). Other intervention names were less common.

The vast majority of trials in "OrthoCarolina" are 32 trials for "All" genders and 1 trials for "Female" genders.

Currently, there are 17 active trials in "OrthoCarolina". 1 are not yet recruiting, 4 are recruiting, 9 are Active, not recruiting, and 3 are Enrolling by invitation. In total, there were 9 completed trials in OrthoCarolina, 2 suspended trials, and 4 terminated clinical trials to date.

Out of the total trials that were conducted in OrthoCarolina, 0 "Phase 1" clinical trials were conducted, 3 "Phase 2" clinical trials and 1 "Phase 3" clinical trials were conducted as well. "Phase 4" trials included 6 trials, and there were also 12 trials that are defined as “Not Applicable".

OrthoCarolina has several departments that took part in Clinical trials: "OrthoCarolina, PA" - 14 trials, "OrthoCarolina Spine Center" - 5 trials, "OrthoCarolina Hip & Knee Center" - 4 trials, "OrthoCarolina Sports Medicine Center" - 2 trials