国立研究開発法人国立循環器病研究センターは、日本の大阪府吹田市にある厚生労働省所管の国立研究開発法人。国立高度専門医療研究センターの一法人で、当センター含め全国に6か所ある専門病院の1つである。厚生労働省直轄の施設等機関であった旧国立循環器病センターから2010年に独立行政法人へ移行した。

During the past decade, National Cerebral and Cardiovascular Center conducted 50 clinical trials. In the 10-year time frame, 50 clinical trials started and 18 clinical trials were completed, i.e. on average, 36% percent of trials that started reached the finish line to date. In the past 5 years, 20 clinical trials started and 11 clinical trials were completed. i.e. 55% of trials that started reached the finish line.

Out of the total clinical trials conducted in "National Cerebral and Cardiovascular Center" #1 sponsor was "National Cerebral and Cardiovascular Center" with 16 trials, followed by "Ministry of Health, Labour and Welfare, Japan" with 6 trials sponsored, "Medtronic Cardiac Rhythm and Heart Failure" with 5 trials sponsored, "Actelion" with 4 trials sponsored and "Abbott Medical Devices" with 4 trials sponsored. Other sponsors include 36 different institutions and companies that sponsored additional 40 trials in total.

In terms of collaborators to trials, out of the total clinical trials conducted in "National Cerebral and Cardiovascular Center" #1 collaborator was "Japan Cardiovascular Research Foundation" with 3 trials as a collaborator, "Medtronic" with 3 trials as a collaborator, "Japan Agency for Medical Research and Development" with 2 trials as a collaborator, "National Cerebral and Cardiovascular Center" with 2 trials as a collaborator and "National Institute of Neurological Disorders and Stroke (NINDS)" with 2 trials as a collaborator. Other collaborators include 46 different institutions and companies that were collaborators in the rest 56 trials.

According to Clinical.Site data, the most researched conditions in "National Cerebral and Cardiovascular Center" are "Heart Failure" (5 trials), "Pulmonary Arterial Hypertension" (4 trials), "Atrial Fibrillation" (3 trials), "Cardiovascular Diseases" (3 trials) and "Coronary Artery Disease" (3 trials). Many other conditions were trialed in "National Cerebral and Cardiovascular Center" in a lesser frequency.

Most popular intervention types in "National Cerebral and Cardiovascular Center" are "Drug" (35 trials), "Device" (25 trials), "Other" (8 trials), "Behavioral" (3 trials) and "Procedure" (3 trials). Other intervention types were less common.

The name of intervention was led by "Placebo" (10 trials), "Macitentan" (2 trials), "Macitentan 10 mg" (2 trials), "17mm MDT-2215 aortic valve bioprosthesis" (1 trials) and "ACT-050089" (1 trials). Other intervention names were less common.

The vast majority of trials in "National Cerebral and Cardiovascular Center" are 74 trials for "All" genders and 1 trials for "Female" genders.

Currently, there are NaN active trials in "National Cerebral and Cardiovascular Center". undefined are not yet recruiting, 17 are recruiting, 12 are Active, not recruiting, and undefined are Enrolling by invitation. In total, there were 29 completed trials in National Cerebral and Cardiovascular Center, undefined suspended trials, and 8 terminated clinical trials to date.

Out of the total trials that were conducted in National Cerebral and Cardiovascular Center, 2 "Phase 1" clinical trials were conducted, 3 "Phase 2" clinical trials and 22 "Phase 3" clinical trials were conducted as well. "Phase 4" trials included 5 trials, and there were also 25 trials that are defined as “Not Applicable".

National Cerebral and Cardiovascular Center has several departments that took part in Clinical trials: "Japan Cardiovascular Research Foundation" - 3 trials