Maple Leaf Research
Toronto, Ontario, Canada
Research foundation in Toronto, Ontario
14 College St, Toronto, ON M5G 1K2
About Maple Leaf Research
- Top Sponsors
- Top Collaborators
- Trials By Phase
- Recruitment Status
- Top Conditions
- Intervention Types
- Top Intervention Names
- Trials By Gender
Lead Sponsor
# Trials
Gilead Sciences
11
Unity Health Toronto
2
Clinical Trials at Maple Leaf Research
During the past decade, Maple Leaf Research conducted 8 clinical trials. In the 10-year time frame, 8 clinical trials started and 8 clinical trials were completed, i.e. on
average, 100% percent of trials that started reached the finish line to date. In the past 5 years, 3 clinical trials started and 0 clinical trials were completed. i.e. 0%
of trials that started reached the finish line.
Trials List
Trail ID
Brief Title
Start Date
Completion Date
Status
Enrollment
Study to Evaluate Switching From Regimens Consisting of a Ritonavir-boosted Protease Inhibitor (PI) and Two Nucleoside Reverse Transcriptase Inhibitors (NRTIs) to a Fixed-dose Tablet Containing Emtricitabine/Rilpivirine/Tenofovir DF
2010-11-01
2014-10-01
Completed
482
Study to Evaluate the Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Positive, Antiretroviral Treatment-Naive Adults
2012-12-26
2017-09-06
Completed
872
Study to Evaluate the Safety and Efficacy of E/C/F/TAF Versus E/C/F/TDF in HIV-1 Positive, Antiretroviral Treatment-Naive Adults
2013-03-12
2018-10-03
Completed
872
Study to Evaluate Switching From a TDF-Containing Combination Regimen to a TAF-Containing Fixed Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Positive Participants
2013-03-27
2020-04-01
Completed
1,443
Phase 3 Open-Label Study to Evaluate Switching From Optimized Stable Antiretroviral Regimens Containing Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Fixed Dose Combination (FDC) Plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive Adults
2013-09-03
2016-07-09
Completed
158
Study to Evaluate Switching From a Regimen Consisting of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate (EFV/FTC/TDF) Fixed Dose Combination (FDC) to Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) FDC in Virologically-Suppressed, HIV-1 Infected Adults
2015-01-26
2019-01-02
Completed
881
Switch Study to Evaluate the Safety and Efficacy of Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) Fixed Dose Combination (FDC) in HIV-1 Positive Adults Who Are Virologically Suppressed on Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate (FTC/RPV/TDF)
2015-01-26
2019-01-09
Completed
632
Switch Study to Evaluate F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed on Regimens Containing ABC/3TC
2015-06-29
2019-03-13
Completed
567
Clinical Trials Sponsors and Collaborators
In terms of collaborators to trials, out of the total clinical trials conducted in "Maple Leaf Research"
#1 collaborator was "CIHR Canadian HIV Trials Network" with 1 trials as a collaborator, "Canadian Institutes of Health Research (CIHR)" with 1 trials as a collaborator and "Gilead Sciences" with 1 trials as a collaborator. Other collaborators include -3 different institutions and companies that were
collaborators in the rest 3 trials.
Clinical Trials Conditions at Maple Leaf Research
According to Clinical.Site data, the most researched conditions in "Maple Leaf Research" are
"HIV Infections" (6 trials), "HIV-1 Infection" (5 trials), "HIV" (3 trials), "HIV-1-infection" (2 trials) and "Acquired Immunodeficiency Syndrome" (1 trials). Many other conditions were trialed in "Maple Leaf Research" in a lesser frequency.
Clinical Trials Intervention Types at Maple Leaf Research
Most popular intervention types in "Maple Leaf Research" are "Drug" (12 trials), "Device" (1 trials) and "Other" (1 trials). Other intervention types were less common.
The name of intervention was led by "E/C/F/TAF" (4 trials), "E/C/F/TDF" (3 trials), "B/F/TAF" (2 trials), "E/C/F/TAF Placebo" (2 trials) and "E/C/F/TDF Placebo" (2 trials). Other intervention names were less common.
Clinical Trials Genders at Maple Leaf Research
The vast majority of trials in "Maple Leaf Research" are
12 trials for "All" genders and 1 trials for "Male" genders.
Clinical Trials Status at Maple Leaf Research
Currently, there are NaN active trials in "Maple Leaf Research".
1 are not yet recruiting,
undefined are recruiting,
3 are Active, not recruiting,
and undefined are Enrolling by invitation.
In total, there were 9 completed trials in Maple Leaf Research,
undefined suspended trials,
and undefined terminated clinical trials to date.
Out of the total trials that were conducted in Maple Leaf Research, 0 "Phase 1"
clinical trials were conducted, 1 "Phase 2" clinical
trials and 10 "Phase 3" clinical trials were conducted as
well. "Phase 4" trials included 1 trials, and there were
also 1 trials that are defined as “Not Applicable".