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The HOPE Clinical Trials Unit

Leicester, United Kingdom
Non-profit organization in Leicester, England
The Lodge, 208 Knighton Rd, Knighton, Leicester LE2 3TT

About The HOPE Clinical Trials Unit


"Hope Against Cancer is Leicestershire and Rutland’s local cancer research charity. We fund cutting-edge research in our area and have made clinical trials available to local people."
  • Top Sponsors
  • Top Collaborators
  • Trials By Phase
  • Recruitment Status
  • Top Conditions
  • Intervention Types
  • Top Intervention Names
  • Trials By Gender
Lead Sponsor
# Trials
Hoffmann-La Roche
3
Institut de Recherches Internationales Servier
2
Merck Sharp & Dohme LLC
2
Total Rows: 3

Clinical Trials at The HOPE Clinical Trials Unit


During the past decade, The HOPE Clinical Trials Unit conducted 6 clinical trials. In the 10-year time frame, 6 clinical trials started and 2 clinical trials were completed, i.e. on average, 33.3% percent of trials that started reached the finish line to date. In the past 5 years, 2 clinical trials started and 0 clinical trials were completed. i.e. 0% of trials that started reached the finish line.
Created with Highcharts 11.1.0TrialsTrials Trend - Last 10 Years1100112200111100110011000000Started TrialsCompleted Trails20162017201820192020202120220123
Trials List
Trail ID
Brief Title
Start Date
Completion Date
Status
Enrollment
A Study of Obinutuzumab in Combination With CHOP Chemotherapy Versus Rituximab With CHOP in Participants With CD20-Positive Diffuse Large B-Cell Lymphoma (GOYA)
2011-07-26
2018-01-31
Terminated
1,418
A Study Evaluating S 95005 Plus Bevacizumab and Capecitabine Plus Bevacizumab in Patients With Previously Untreated Colorectal Cancer Who Are Non-eligible for Intensive Therapy
2016-04-29
2020-09-01
Completed
154
An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
2018-05-08
2024-11-30
Recruiting
280
Phase III Study in First-line Treatment of Patients With Metastatic Colorectal Cancer Who Are Not Candidate for Intensive Therapy.
2019-03-21
2022-10-01
Completed
874
A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of RO7227166 in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab Administered in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
2019-08-13
2025-03-31
Recruiting
420
Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)
2021-06-18
2028-07-21
Recruiting
800
Study of Pembrolizumab/Vibostolimab Coformulation (MK-7684A) in Combination With Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (MK-7684A-007/KEYVIBE-007)
2022-03-24
2027-09-27
Recruiting
700

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Clinical Trials Sponsors and Collaborators


In terms of collaborators to trials, out of the total clinical trials conducted in "The HOPE Clinical Trials Unit" #1 collaborator was "ADIR, a Servier Group company" with 2 trials as a collaborator and "Fondazione Italiana Linfomi ONLUS" with 1 trials as a collaborator. Other collaborators include -2 different institutions and companies that were collaborators in the rest 2 trials.
Created with Highcharts 11.1.0Top Leading SponsorsHoffmann-La Roche: 3Hoffmann-La Roche: 3Institut de RecherchesInternationales Servier:2Institut de RecherchesInternationales Servier:2Merck Sharp & Dohme LLC: 2Merck Sharp & Dohme LLC: 2

Created with Highcharts 11.1.0Top CollaboratorsADIR, a Servier Groupcompany: 2ADIR, a Servier Groupcompany: 2Fondazione ItalianaLinfomi ONLUS: 1Fondazione ItalianaLinfomi ONLUS: 1

Clinical Trials Conditions at The HOPE Clinical Trials Unit


According to Clinical.Site data, the most researched conditions in "The HOPE Clinical Trials Unit" are "Metastatic Colorectal Cancer" (2 trials), "Breast Neoplasms" (1 trials), "Diffuse Large B-Cell Lymphoma" (1 trials), "Lymphoma, Non-Hodgkin" (1 trials) and "Metastatic Non-Small Cell Lung Cancer" (1 trials). Many other conditions were trialed in "The HOPE Clinical Trials Unit" in a lesser frequency.

Clinical Trials Intervention Types at The HOPE Clinical Trials Unit


Most popular intervention types in "The HOPE Clinical Trials Unit" are "Drug" (7 trials) and "Biological" (3 trials). Other intervention types were less common.
The name of intervention was led by "Obinutuzumab" (3 trials), "Glofitamab" (2 trials), "Tocilizumab" (2 trials), "89Zr-Df-IAB22M2C" (1 trials) and "Atezolizumab" (1 trials). Other intervention names were less common.

Clinical Trials Genders at The HOPE Clinical Trials Unit


The vast majority of trials in "The HOPE Clinical Trials Unit" are 7 trials for "All" genders.

Clinical Trials Status at The HOPE Clinical Trials Unit


Currently, there are NaN active trials in "The HOPE Clinical Trials Unit". undefined are not yet recruiting, 4 are recruiting, undefined are Active, not recruiting, and undefined are Enrolling by invitation. In total, there were 2 completed trials in The HOPE Clinical Trials Unit, undefined suspended trials, and 1 terminated clinical trials to date.
Out of the total trials that were conducted in The HOPE Clinical Trials Unit, 2 "Phase 1" clinical trials were conducted, 2 "Phase 2" clinical trials and 4 "Phase 3" clinical trials were conducted as well. "Phase 4" trials included 0 trials, and there were also 0 trials that are defined as “Not Applicable".
Created with Highcharts 11.1.0Trials By PhasePhase 3: 4Phase 3: 4Phase 1: 2Phase 1: 2Phase 2: 2Phase 2: 2

Created with Highcharts 11.1.0Trials StatusRecruiting: 4Recruiting: 4Completed: 2Completed: 2Terminated: 1Terminated: 1