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Great Ormond Street Hospital

London, United Kingdom
Hospital in London, England
Great Ormond Street, London WC1N 3JH
389 Beds

About Great Ormond Street Hospital


Great Ormond Street Hospital is a children's hospital located in the Bloomsbury area of the London Borough of Camden, and a part of Great Ormond Street Hospital for Children NHS Foundation Trust.
There are 389 beds in Great Ormond Street Hospital.
  • Top Sponsors
  • Top Collaborators
  • Trials By Phase
  • Recruitment Status
  • Top Conditions
  • Intervention Types
  • Top Intervention Names
  • Trials By Gender
Lead Sponsor
# Trials
Great Ormond Street Hospital for Children NHS Foundation Trust
47
Children's Cancer and Leukaemia Group
35
Institute of Child Health
9
Shire
9
Eli Lilly and Company
8
University College, London
8
Baxalta now part of Shire
6
BioMarin Pharmaceutical
6
Sarepta Therapeutics, Inc.
6
PTC Therapeutics
5
University of Birmingham
5
Total Rows: 100

Clinical Trials at Great Ormond Street Hospital


During the past decade, Great Ormond Street Hospital conducted 180 clinical trials. In the 10-year time frame, 180 clinical trials started and 57 clinical trials were completed, i.e. on average, 31.7% percent of trials that started reached the finish line to date. In the past 5 years, 68 clinical trials started and 37 clinical trials were completed. i.e. 54.4% of trials that started reached the finish line.
Created with Highcharts 11.1.0TrialsTrials Trend - Last 10 Years1919303017172323232330301818181811112211224411111010121211114400Started TrialsCompleted Trails2015201620172018201920202021202220232024010203040
Trials List
Trail ID
Brief Title
Start Date
Completion Date
Status
Enrollment
Surgery in Treating Patients With Neuroblastoma
1994-12-01
Unknown status
210
Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma
1995-05-01
Unknown status
100
Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Non-Hodgkin's Lymphoma
2000-05-01
Unknown status
500
Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia
1999-05-01
2009-12-01
Completed
350
Radiation Therapy and Tamoxifen in Treating Children With Newly Diagnosed Brain Stem Glioma
1999-08-01
Unknown status
Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter
1999-02-01
Unknown status
1,360
Combination Chemotherapy With or Without Radiation Therapy and Peripheral Stem Cell Transplant in Treating Children With Hodgkin's Lymphoma
2000-01-01
Unknown status
260
Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors
2000-01-01
2011-04-01
Completed
50

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Clinical Trials Sponsors and Collaborators


Out of the total clinical trials conducted in "Great Ormond Street Hospital" #1 sponsor was "Great Ormond Street Hospital for Children NHS Foundation Trust" with 47 trials, followed by "Children's Cancer and Leukaemia Group" with 35 trials sponsored, "Institute of Child Health" with 9 trials sponsored, "Shire" with 9 trials sponsored and "Eli Lilly and Company" with 9 trials sponsored. Other sponsors include 211 different institutions and companies that sponsored additional 125 trials in total.
In terms of collaborators to trials, out of the total clinical trials conducted in "Great Ormond Street Hospital" #1 collaborator was "Great Ormond Street Hospital for Children NHS Foundation Trust" with 17 trials as a collaborator, "University College, London" with 13 trials as a collaborator, "National Institute for Health Research, United Kingdom" with 9 trials as a collaborator, "Newcastle-upon-Tyne Hospitals NHS Trust" with 7 trials as a collaborator and "University Hospital Southampton NHS Foundation Trust" with 6 trials as a collaborator. Other collaborators include 349 different institutions and companies that were collaborators in the rest 310 trials.
Created with Highcharts 11.1.0Top Leading SponsorsGreat Ormond StreetHospital for ChildrenNHS Foundation Trust:47Great Ormond StreetHospital for ChildrenNHS Foundation Trust:47Children's Cancer andLeukaemia Group: 35Children's Cancer andLeukaemia Group: 35Institute of Child Health: 9Institute of Child Health: 9Shire: 9Shire: 9Eli Lilly and Company: 8Eli Lilly and Company: 8University College, London: 8University College, London: 8Baxalta now part of Shire: 6Baxalta now part of Shire: 6BioMarin Pharmaceutical: 6BioMarin Pharmaceutical: 6Sarepta Therapeutics, Inc.: 6Sarepta Therapeutics, Inc.: 6PTC Therapeutics: 5PTC Therapeutics: 5

Created with Highcharts 11.1.0Top CollaboratorsGreat Ormond StreetHospital for ChildrenNHS Foundation Trust:17Great Ormond StreetHospital for ChildrenNHS Foundation Trust:17University College, London: 13University College, London: 13National Institute forHealth Research, UnitedKingdom: 9National Institute forHealth Research, UnitedKingdom: 9Newcastle-upon-TyneHospitals NHS Trust: 7Newcastle-upon-TyneHospitals NHS Trust: 7University HospitalSouthampton NHSFoundation Trust: 6University HospitalSouthampton NHSFoundation Trust: 6Alder Hey Children'sNHS Foundation Trust: 4Alder Hey Children'sNHS Foundation Trust: 4Barts & The London NHS Trust: 3Barts & The London NHS Trust: 3Birmingham Women'sand Children's NHSFoundation Trust: 3Birmingham Women'sand Children's NHSFoundation Trust: 3Cambridge UniversityHospitals NHSFoundation Trust: 3Cambridge UniversityHospitals NHSFoundation Trust: 3Cancer Research UK: 3Cancer Research UK: 3

Clinical Trials Conditions at Great Ormond Street Hospital


According to Clinical.Site data, the most researched conditions in "Great Ormond Street Hospital" are "Duchenne Muscular Dystrophy" (17 trials), "Brain and Central Nervous System Tumors" (15 trials), "Neuroblastoma" (13 trials), "Cystic Fibrosis" (8 trials) and "Hemophilia A" (8 trials). Many other conditions were trialed in "Great Ormond Street Hospital" in a lesser frequency.

Clinical Trials Intervention Types at Great Ormond Street Hospital


Most popular intervention types in "Great Ormond Street Hospital" are "Drug" (195 trials), "Biological" (52 trials), "Procedure" (48 trials), "Other" (44 trials) and "Radiation" (23 trials). Other intervention types were less common.
The name of intervention was led by "Placebo" (26 trials), "radiation therapy" (19 trials), "vincristine sulfate" (18 trials), "carboplatin" (16 trials) and "cyclophosphamide" (16 trials). Other intervention names were less common.

Clinical Trials Genders at Great Ormond Street Hospital


The vast majority of trials in "Great Ormond Street Hospital" are 285 trials for "All" genders and 39 trials for "Male" genders.

Clinical Trials Status at Great Ormond Street Hospital


Currently, there are 104 active trials in "Great Ormond Street Hospital". 3 are not yet recruiting, 64 are recruiting, 33 are Active, not recruiting, and 4 are Enrolling by invitation. In total, there were 131 completed trials in Great Ormond Street Hospital, 1 suspended trials, and 27 terminated clinical trials to date.
Out of the total trials that were conducted in Great Ormond Street Hospital, 49 "Phase 1" clinical trials were conducted, 108 "Phase 2" clinical trials and 108 "Phase 3" clinical trials were conducted as well. "Phase 4" trials included 5 trials, and there were also 45 trials that are defined as “Not Applicable".
Created with Highcharts 11.1.0Trials By PhasePhase 2: 108Phase 2: 108Phase 3: 108Phase 3: 108Phase 1: 49Phase 1: 49Not Applicable: 45Not Applicable: 45Phase 4: 5Phase 4: 5Early Phase 1: 2Early Phase 1: 2

Created with Highcharts 11.1.0Trials StatusCompleted: 131Completed: 131Recruiting: 64Recruiting: 64Unknown status: 57Unknown status: 57Active, not recruiting: 33Active, not recruiting: 33Terminated: 27Terminated: 27Enrolling by invitation: 4Enrolling by invitation: 4Not yet recruiting: 3Not yet recruiting: 3Withdrawn: 3Withdrawn: 3No longer available: 1No longer available: 1Suspended: 1Suspended: 1

Departments of Great Ormond Street Hospital


Great Ormond Street Hospital has several departments that took part in Clinical trials: "Somers Clinical Research Facility, Great Ormond Street Hospital" - 3 trials, "Great Ormond Street Hospital; Dept. Of Pediatric Oncology" - 3 trials, "Great Ormond Street Hospital For Children; Neurology" - 2 trials, "Great Ormond Street Hospital, Paediatric Intensive Care" - 2 trials, "Great Ormond Street Hospital - Department of Haematology" - 2 trials, "Great Ormond street Hospital for Children NHS Foundation Trust; Haemophilia Centre" - 2 trials