The Sheffield Children's Hospital is a healthcare facility for children in Broomhill, Sheffield, South Yorkshire, England. It is managed by the Sheffield Children's NHS Foundation Trust.

During the past decade, Children's Hospital - Sheffield conducted 72 clinical trials. In the 10-year time frame, 72 clinical trials started and 18 clinical trials were completed, i.e. on average, 25% percent of trials that started reached the finish line to date. In the past 5 years, 27 clinical trials started and 11 clinical trials were completed. i.e. 40.7% of trials that started reached the finish line.

Out of the total clinical trials conducted in "Children's Hospital - Sheffield" #1 sponsor was "Children's Cancer and Leukaemia Group" with 33 trials, followed by "Sheffield Children's NHS Foundation Trust" with 20 trials sponsored, "BioMarin Pharmaceutical" with 6 trials sponsored, "Eli Lilly and Company" with 5 trials sponsored and "Alexion" with 5 trials sponsored. Other sponsors include 75 different institutions and companies that sponsored additional 63 trials in total.

In terms of collaborators to trials, out of the total clinical trials conducted in "Children's Hospital - Sheffield" #1 collaborator was "Sheffield Children's NHS Foundation Trust" with 7 trials as a collaborator, "University of Sheffield" with 6 trials as a collaborator, "Cambridge University Hospitals NHS Foundation Trust" with 4 trials as a collaborator, "Children's Cancer and Leukaemia Group" with 4 trials as a collaborator and "Newcastle-upon-Tyne Hospitals NHS Trust" with 4 trials as a collaborator. Other collaborators include 122 different institutions and companies that were collaborators in the rest 111 trials.

According to Clinical.Site data, the most researched conditions in "Children's Hospital - Sheffield" are "Brain and Central Nervous System Tumors" (15 trials), "Achondroplasia" (10 trials), "Neuroblastoma" (10 trials), "Sarcoma" (7 trials) and "Lymphoma" (5 trials). Many other conditions were trialed in "Children's Hospital - Sheffield" in a lesser frequency.

Most popular intervention types in "Children's Hospital - Sheffield" are "Drug" (87 trials), "Procedure" (30 trials), "Biological" (24 trials), "Other" (23 trials) and "Radiation" (23 trials). Other intervention types were less common.

The name of intervention was led by "radiation therapy" (20 trials), "carboplatin" (18 trials), "vincristine sulfate" (17 trials), "Placebo" (16 trials) and "cyclophosphamide" (15 trials). Other intervention names were less common.

The vast majority of trials in "Children's Hospital - Sheffield" are 142 trials for "All" genders and 5 trials for "Male" genders.

Currently, there are 36 active trials in "Children's Hospital - Sheffield". 1 are not yet recruiting, 25 are recruiting, 9 are Active, not recruiting, and 1 are Enrolling by invitation. In total, there were 64 completed trials in Children's Hospital - Sheffield, 1 suspended trials, and 5 terminated clinical trials to date.

Out of the total trials that were conducted in Children's Hospital - Sheffield, 5 "Phase 1" clinical trials were conducted, 36 "Phase 2" clinical trials and 50 "Phase 3" clinical trials were conducted as well. "Phase 4" trials included 8 trials, and there were also 27 trials that are defined as “Not Applicable".

Children's Hospital - Sheffield has several departments that took part in Clinical trials: "Clinical Research Facility, Sheffield Childrens Hospital" - 2 trials